Acetylcysteine

Also known as / Brand Names

Acetylcysteine is also known as N-acetylcysteine (NAC). Common brand names include Mucomyst, Acetadote, Fluimucil, Parvolex, and Mucolator. It is available in various forms such as oral tablets, effervescent tablets, oral solutions, and intravenous injections.

Product Introduction

Acetylcysteine is a medication widely used for its mucolytic and antioxidant properties. It works by thinning and loosening mucus in the airways, thereby making it easier to cough out and breathe more comfortably. It is primarily used to treat conditions such as chronic bronchitis, cystic fibrosis, and other respiratory illnesses involving thick mucus. Additionally, acetylcysteine is used in hospitals as an antidote for acetaminophen (paracetamol) overdose due to its ability to replenish glutathione levels in the liver and prevent toxicity.

Acetylcysteine is available in oral and inhalation forms for mucolytic therapy, while the intravenous form is administered in cases of drug overdose. It has gained popularity as a dietary supplement due to its role in antioxidant defense and potential benefits in managing oxidative stress-related conditions, though such uses are still under research.

Uses of Acetylcysteine

• Treatment of respiratory conditions with thick mucus (e.g., chronic bronchitis, COPD, cystic fibrosis)
• Management of acetaminophen (paracetamol) overdose
• Supportive therapy for contrast-induced nephropathy
• As an antioxidant supplement in specific clinical and research settings

Benefits of Acetylcysteine

• Helps break down and thin mucus, improving respiratory function
• Protects the liver in acetaminophen overdose by restoring glutathione levels
• Potential protective effect on the kidneys in patients undergoing contrast imaging procedures
• Acts as an antioxidant and may help in managing oxidative stress

Side Effects of Acetylcysteine

Most people tolerate acetylcysteine well, but some may experience side effects, especially when taken orally or via inhalation. These can include:

• Nausea or vomiting
• Diarrhea
• Foul-smelling breath or aftertaste
• Stomach upset
• Allergic reactions (rash, hives, itching, especially with IV form)
• Bronchospasm or throat irritation (inhalation form)

Safety Advice

Condition	Advice
Pregnancy	SAFE IF PRESCRIBED – Acetylcysteine is generally considered safe to use during pregnancy if recommended by a doctor. Clinical evidence shows no known risk to the fetus.
Breastfeeding	SAFE IF PRESCRIBED – Acetylcysteine is unlikely to harm the nursing infant. It is considered safe during breastfeeding when used as advised.
Driving	CAUTION – Acetylcysteine does not typically affect driving, but dizziness or drowsiness has been reported in some users. Avoid driving if affected.
Kidney	SAFE IF PRESCRIBED – No dose adjustment is usually required. It may even help reduce kidney injury risk in specific medical procedures.
Liver	SAFE IF PRESCRIBED – Acetylcysteine supports liver detoxification in overdose cases and is considered beneficial to liver health when used appropriately.

Important Reminder

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Acetylcysteine only for the indication prescribed.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.