Ajovy – Medicine Information

Ajovy

Also Known As / Brand Names

Ajovy is the brand name for Fremanezumab-vfrm, a prescription monoclonal antibody medicine used to prevent migraines. It is manufactured by Teva Pharmaceuticals and is available as a prefilled syringe or autoinjector. Ajovy targets the calcitonin gene-related peptide (CGRP), which is believed to play a key role in migraine attacks.

Product Introduction

Ajovy (Fremanezumab) is part of a newer class of biologics designed to reduce the frequency of migraine headaches. It works by binding to CGRP, a neuropeptide involved in the transmission of pain and dilation of blood vessels in the brain during migraine episodes. By blocking this peptide, Ajovy helps reduce the number of migraine days per month.

Ajovy is administered via subcutaneous injection and can be dosed once a month (225 mg) or quarterly (675 mg), depending on patient preference and physician guidance. It is well-suited for adults who experience episodic or chronic migraines and have not responded well to oral preventive medications.

Uses of Ajovy

  • Preventive treatment of episodic migraine in adults
  • Preventive treatment of chronic migraine in adults

Benefits of Ajovy

  • Reduces the number of monthly migraine days
  • Flexible dosing – monthly or quarterly options
  • Convenient self-injection with autoinjector
  • Non-addictive and not associated with medication-overuse headaches
  • Generally well-tolerated with a low risk of serious side effects

Side Effects of Ajovy

Ajovy is usually well-tolerated. Common side effects may include:

  • Injection site reactions (pain, redness, swelling, itching)
  • Allergic reactions such as rash or itching (rare)
  • Fatigue or dizziness in some individuals
  • Constipation
  • Muscle pain or cramps

Serious allergic reactions (anaphylaxis) are rare but possible. Patients should seek immediate medical help if they develop swelling of the face, tongue, or throat, or difficulty breathing after injection.

Safety Advice

Condition Advice
Pregnancy CAUTION – There is limited data on use in pregnancy. Ajovy should be used only if the benefits clearly outweigh potential risks. Discuss with your doctor.
Breastfeeding CAUTION – It is not known whether Fremanezumab is excreted in human milk. Use only if clearly needed and under medical advice.
Driving SAFE – Ajovy does not affect your ability to drive or operate machinery. If dizziness occurs, avoid such activities until you feel normal.
Kidney SAFE – No dose adjustment is needed in people with kidney problems. Ajovy is not metabolized by the kidneys.
Liver SAFE – No dose adjustment is required for liver conditions. Ajovy is not processed through the liver in a way that requires caution.

Important Reminder

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Ajovy only for the indication prescribed.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.