Aldactone
Also known as / Brand Names:
Generic Name: Spironolactone
Brand Names: Aldactone, CaroSpir (oral suspension), Spironol
Product Introduction:
Aldactone is a prescription medication that belongs to a class of drugs known as potassium-sparing diuretics or aldosterone antagonists. It is primarily used to treat conditions such as heart failure, high blood pressure (hypertension), and conditions involving fluid retention (edema). Additionally, it is sometimes prescribed for managing hormonal imbalances like hyperaldosteronism and certain cases of acne or hirsutism in women.
The active ingredient, spironolactone, works by blocking the action of aldosterone, a hormone that causes the body to retain sodium and water. By doing so, it promotes the elimination of excess fluid while retaining potassium, which is vital for heart and muscle function.
Uses of Aldactone:
- High blood pressure (hypertension)
- Heart failure (especially with reduced ejection fraction)
- Edema associated with liver cirrhosis or nephrotic syndrome
- Primary hyperaldosteronism (diagnosis and treatment)
- Hormonal acne and hirsutism in females (off-label use)
- Polycystic ovary syndrome (PCOS) – as adjunctive therapy (off-label)
Benefits of Aldactone:
- Reduces blood pressure and decreases risk of stroke and heart attacks
- Improves survival and reduces hospitalizations in heart failure patients
- Promotes loss of excess fluid without causing potassium loss
- Manages hormonal acne and male-pattern hair growth in women
- Helps in correcting potassium deficiency and hyperaldosteronism
Side Effects of Aldactone:
- High potassium levels (hyperkalemia)
- Breast tenderness or enlargement (gynecomastia)
- Menstrual irregularities
- Fatigue and dizziness
- Gastrointestinal upset (nausea, vomiting, diarrhea)
- Dehydration and low sodium levels
- Headache or rash (rare)
Contact your doctor immediately if you experience symptoms of high potassium (muscle weakness, irregular heartbeat) or signs of severe dehydration.
Safety Advice:
| Condition | Advice |
|---|---|
| Pregnancy | Unsafe – May affect fetal development. Avoid use unless prescribed specifically. |
| Breastfeeding | Caution – May pass into breast milk. Consult your doctor. |
| Driving | Caution – May cause dizziness or drowsiness. Avoid driving if affected. |
| Kidney Disease | Unsafe – Not recommended in patients with severe kidney impairment or high potassium levels. |
| Liver Disease | Caution – Dose adjustment may be required. Monitor liver function tests. |
How to Use Aldactone:
Take Aldactone exactly as prescribed by your healthcare provider. It is usually taken once or twice daily, with or without food. Taking it with food may reduce stomach upset. Try to take it at the same time each day for best results.
Do not increase or decrease your dose without consulting your doctor. Regular monitoring of potassium levels, kidney function, and blood pressure is recommended during therapy.
Drug Interactions:
Aldactone may interact with several medications, including:
- Other potassium-sparing diuretics (e.g., amiloride, triamterene)
- ACE inhibitors or ARBs (e.g., lisinopril, losartan)
- NSAIDs (e.g., ibuprofen, naproxen)
- Digoxin
- Lithium
- Heparin and potassium supplements
Always inform your doctor about all the medications and supplements you are taking to avoid harmful interactions.
Storage and Handling:
- Store at room temperature away from moisture and heat.
- Keep in a tightly closed container.
- Keep out of reach of children and pets.
Important Reminder:
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Aldactone only for the indication prescribed.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.