Alfuzosin
Also known as / Brand Names:
Generic Name: Alfuzosin
Brand Names: Uroxatral, Alfusin, Alfoo, Xatral
Product Introduction:
Alfuzosin is an alpha-blocker used to treat symptoms of an enlarged prostate, a condition known as benign prostatic hyperplasia (BPH). It works by relaxing the muscles in the bladder neck and prostate, making it easier to urinate and relieving symptoms like weak stream, frequent urination, and incomplete bladder emptying.
Unlike other alpha-blockers, Alfuzosin is often preferred due to its extended-release formulation that helps maintain steady blood levels throughout the day, improving comfort and compliance. However, it does not shrink the prostate or cure BPH — it only helps relieve the symptoms.
Uses of Alfuzosin:
- Treatment of benign prostatic hyperplasia (BPH) in men
- Helps in relieving urinary symptoms such as difficulty in urination, hesitancy, dribbling, and frequent urination
Benefits of Alfuzosin:
- Improves urine flow by relaxing muscles in the prostate and bladder
- Reduces urgency, frequency, and nocturia (night-time urination)
- Improves quality of life in men with BPH
- Extended-release form allows once-daily dosing
Side Effects of Alfuzosin:
- Dizziness or light-headedness, especially when standing up
- Headache
- Fatigue
- Stomach pain or indigestion
- Runny or stuffy nose
- Low blood pressure (especially with other BP medications)
- Rare: Irregular heartbeat, priapism (prolonged erection)
Safety Advice:
| Condition | Safety Advice |
|---|---|
| Pregnancy | Unsafe – Alfuzosin is not indicated for use in women and should not be used during pregnancy. |
| Breastfeeding | Not applicable – This medicine is not used in women and hence breastfeeding advice is not relevant. |
| Driving | Caution – Alfuzosin may cause dizziness or drowsiness. Avoid driving until you know how it affects you. |
| Kidney | Caution – Use with care in people with severe kidney impairment. Dose adjustment may be necessary. |
| Liver | Unsafe – Should not be used in patients with moderate to severe liver impairment due to increased risk of side effects. |
How to Use Alfuzosin:
Take Alfuzosin exactly as prescribed by your doctor. It is typically taken once daily, after the same meal each day to improve absorption and reduce side effects. Swallow the tablet whole with water. Do not crush or chew the tablet, as this may cause too much of the drug to be released at once.
Interactions:
Alfuzosin may interact with other medications. Inform your doctor if you are taking:
- Other alpha-blockers (e.g., tamsulosin)
- Nitrates for chest pain (can cause dangerous drop in BP)
- Antifungals like ketoconazole or itraconazole
- HIV protease inhibitors (e.g., ritonavir)
- Antibiotics like erythromycin or clarithromycin
Storage Instructions:
Store Alfuzosin tablets at room temperature (20°C to 25°C), away from light and moisture. Keep out of reach of children and pets. Do not use expired medication.
Important Reminder:
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Alfuzosin only for the indication prescribed.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.